Accession Number: pdtdbl00232

Details of the Ligand

Ligand Name : Girinimbine
Systematic Names : Girinimbine; 3,3,5-trimethyl-11H-pyrano[3,2-a]carbazole; 3,3,5-trimethyl-3,11-dihydropyrano[3,2-a]carbazole
Molecular Formula : C18H17NO
Molecular Weight : g/mol
IUPAC Name : 3,3,5-trimethyl-11H-pyrano[3,2-a]carbazole
Canonical SMILES : CC1=C2C(=C3C(=C1)C4=CC=CC=C4N3)C=CC(O2)(C)C
Ligand Description :

Girinimbine is a carbazole alkaloid isolated from the curry tree (Murraya koenigii) along with the related alkaloids Mahanimbine, Koenimbine, Isomahanine, Mahanine, and others. It acts as a anti-cancer agent.

A 2011 study of girinimbine found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells in vitro.
Related Plants :
Curry leaf
Ligand Related Dockings :
NA
Ligand References :
  1. https://pubchem.ncbi.nlm.nih.gov/compound/Girinimbine
  2. https://en.wikipedia.org/wiki/Girinimbine
  3. https://www.hindawi.com/journals/ecam/2013/689865/
Girinimbine

Click the image to enlarge